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[7] [8] Readers should check the current NICE Technology Appraisal for tirzepatide in weight management and the emc SmPC (medicines.org.uk) for the most up-to-date information on its licensed indications and eligibility criteria in the UK, as guidance may be updated

Some data suggest neuroprotective properties, and there are ongoing randomised trials among patients with neurological and psychiatric disorders (NCT04466345)

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A solution of TPE-CHO (180 mg, 0.5 mmol) and malononitrile (66 mg, 1 mmol) in dry EtOH (10 mL) was refluxed under nitrogen for 24 h