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Topiramate (Topamax): Evolving Role in Weight Reduction Management: A Narrative Review

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Similar content being viewed by others Subjects Introduction Glucagon-like peptide-1 (GLP-1) is an insulinotropic 1,2 incretin derived from preproglucagon (PPG), which was first identified in the intestine 3

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The proposed mechanism involves controlling glutamate release in the synaptic cleft, modulating NMDA receptor stimulation, affecting excitatory amino acid transporter (EAAT)-mediated reuptake, and maintaining the glutamate/glutamine cycle within astrocytes

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