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Annals of internal medicine

Usual care, or UC (ie, physical therapy, pain management, lifestyle changes, and possible medications), amounted to 9.5 QALY compared with 9.75 for diet and exercise

Berberine has real research behind its role in supporting healthy blood sugar and metabolism not as "nature's Ozempic," but as a legitimate metabolic support, which is why a berberine formula honest about what it does is different from the trend-chasing products making outsized claims