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The most common side effects include: There is also a risk of complications of diabetic eye disease (diabetic retinopathy)
Patients were excluded if they had chronic pain due to other causes or previous knee surgery
Both drugs independently increase heart rate and can elevate blood pressurecombined use amplifies cardiovascular strain, particularly in patients with hypertension or cardiac history
Though these side effects are rare, they are important to know about
Whilst back pain is not listed among the common adverse reactions in the MHRA-approved Summary of Product Characteristics, some patients have reported experiencing it during treatment
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