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These CAFs uptake OxLDL and activate the PPARG-FABP4 axis, leading to ANGPTL4 secretion that promotes CD8+ T cell exhaustion
En contraparte, en la Diabetes mellitus tipo 2 (DM2) se encuentran alteraciones en la funcin de las incretinas con resistencia a sus efectos, lo que se relaciona con un peor perfil cardiometablico y riesgo cardiovascular
Neuroprotection in the laboratory is studied primarily in rodent models of transient brain ischaemia but not in primate models
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