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It was first isolated and characterised by Professor Predrag Sikiric and his research group at the University of Zagreb in the early 1990s, with the foundational paper published in the Journal of Physiology (Paris) in 1993

doi: 10.1021/acs.jmedchem.5b00726 61 Eli Lilly and Company

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That question sent him on three years of research into human energy production and phototherapy