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Low levels of melanin mean that the skin is highly susceptible to DNA damage with excess sun exposure

Mitochondrial malate dehydrogenase (MDH2) converts 2-oxoglutarate to 2-HG while alcohol dehydrogenase iron containing 1 (encoded by the ADHFE1 gene) converts GHB to 2-HG and succinic semialdehyde (SSA)

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The curcumin in turmeric has anti-inflammatory properties that may indirectly aid metabolic health

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