Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (under the brand name Ozempic), chronic weight management (Wegovy), and cardiovascular risk reduction in adults with established cardiovascular disease and obesity or overweight
Matched tumor/surrounding tumor tissues were obtained and RNA-seq was performed
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Inflammation and endothelial dysfunction in diabetes: mechanistic links and therapeutic opportunities
At this point, we suggest to better investigate the effect of different dosages by a randomized, double-blind placebo-controlled, longitudinal prospective trial, with three arms (placebo, ALCAR 3 g/day, ALCAR 1.5 g/day) and long-term follow up (12 months)