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Butyrate ameliorates quinolinic acidinduced cognitive decline in obesity models
Clinical trial context: According to the manufacturer, the STEP 1 trial demonstrated 14.9% average body weight loss over 68 weeks among participants who also followed reduced-calorie diets and increased physical activity
doi:10.1002/ptr.1953
Cnop M, Foufelle F, Velloso LA
Small molecules that trigger ferroptosis identified thus far include agents that inhibit GPX4 directly, molecules that deplete the GPX4 cofactor glutathione, and compounds that oxidize iron 1,9,11,12
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