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Inhibition of GLP-1 action with Exendin-9,39 after RYGB accelerates gastric emptying (45)
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Int J Mol Sci 20:1074
At 36 weeks, 63% of adults with overweight or obesity and type 2 diabetes treated with retatrutide lost at least 15% of their body weight, compared to 40% achieving that level with 15 mg tirzepatide at 40 weeks
Contact your healthcare provider promptly if you experience: Persistent dizziness lasting more than a few seconds when standing Fainting or near-fainting episodes Falls or loss of balance attributed to dizziness Chest pain, palpitations, or irregular heartbeat accompanying low blood pressure symptoms Severe or persistent nausea, vomiting, or diarrhea leading to dehydration Confusion, difficulty concentrating, or unusual fatigue Blood pressure readings consistently below 90/60 mmHg with symptoms New or worsening shortness of breath Seek emergency care (call 911) if you experience: Loss of consciousness Chest pain or pressure Severe shortness of breath Confusion or altered mental status Seizures Signs of stroke (facial drooping, arm weakness, speech difficulty) Your healthcare provider may need to adjust your GLP-1 medication dose, modify or discontinue antihypertensive medications, or investigate other potential causes of hypotension
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