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The overall safety profile appears favorable based on available data, though individual responses vary

Tumor-suppressive effect of metformin via the regulation of M2 macrophages and myeloid-derived suppressor cells in the tumor microenvironment of colorectal cancer

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Limit your drinking and monitor liver health when taking this drug

doi: 10.1111/dom.15058 85 GersteinHCSattarNRosenstockJRamasundarahettigeCPratleyRLopesRDet al