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A note on choline Very high choline intake can raise TMAO, a marker linked to cardiovascular risk in observational studies
There are zero published human clinical trials on Dihexa as of 2026, making the clinical relevance of the animal potency entirely speculative
If retatrutide reduces major cardiovascular events (like semaglutide did in SELECT), the heart rate increase will be viewed as a pharmacologically interesting but clinically irrelevant side effect
Unlike Qsymia, GLP-1 medications target hormonal regulation of appetite and metabolism, offering not just weight reduction but ancillary benefits like improved glucose control
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