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The pivotal role of central dysfunctional, insulin-resistant adipose tissue to the evolution of advanced fibrosis in patients with T2D and NAFLD, beyond body mass index (BMI) or steatosis, has been well established [5]
Neuron 2017;96:461-75.ArticlePubMedPMC 89
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A combination of effects on CV risk factors and direct effect on the process of atherosclerosis are supported by preclinical studies where GLP-1RA showed anti-atherosclerotic and anti-inflammatory effects and improved endothelial function [73]
