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GPX has long been known to be a player in H 2 O 2 metabolism in mammalian cells, but only began to be seriously studied in plants following the description of sequences homologous to the animal enzymes in the 1990s
10.1007/s00253-023-12996-1 46 WangM.ChenZ.YangL.DingL
In summary, arginine depletion may be a feasible approach for cancer treatment because of the anti-cancer effects reported in pre-clinical studies, the low adverse reactions and the treatment-achieved stable disease in clinical trials of advanced stage cancers
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