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Titration schedule: Retatrutide's glucagon receptor activation provides an additional thermogenic effect absent from semaglutide and tirzepatide
The irony, as you point out, is that this same rigidness does not apply to other medications that can be prescribed in a more flexible manner
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These may include injection site discomfort or mild swelling, occasional headache, or mild fatigue, particularly with appropriate dosing and patient preparation including adequate hydration
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