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9 Perspectives: strategy models, research gaps, and defining outcomes There are currently no established guidelines for how to best combine or sequence GLP-1 RAs with psychological or lifestyle interventions

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Publisher's Note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Age-related changes in kidney function and body composition mean that elderly patients may experience slightly prolonged drug exposure, though specific dose adjustments based solely on age are typically not required