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Tirzepatide is a first-in-class dual incretin receptor agonist a single molecule that activates both the GIP (glucose-dependent insulinotropic polypeptide) and the GLP-1 (glucagon-like peptide-1) receptors, which is why it is often nicknamed a twincretin. [7] By engaging two incretin pathways it enhances glucose-dependent insulin secretion, promotes satiety, and delays gastric emptying, producing large effects on both glycemic control and bodyweight
& Edwards, K
Studies have observed that female mice exposed to DSIP for 5 consecutive days of every month starting at the age of 3 months till their death exhibited a 2.6-fold reduction in the development of tumors compared to parallel control groups
While its generally well tolerated, people with existing liver conditions should only use it under medical supervision
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