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Numerous clinical trials are underway investigating obesity assets in co-morbidities, e.g., MACE-3 components, heart failure, sleep apnea, chronic kidney disease (CKD), NASH/MASH, osteoarthritis of knee, with several recent positive, high-profile readouts, including semaglutide in CKD and HFpEF
Because both influence overlapping systemsappetite, metabolism, and the nervous systemthere is a need for more research
Whether these differences can explain metabolic outcomes will be explored in detail below (Figure 2)
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