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In March 2023 it was recommended for the treatment of obesity in specific circumstances

10.1038/551S33a 43 GuoY.TaoM.JiangM

Hormones, nerve function, blood vessel health, stress, and sleep all play roles

GLP-1 is a peptide-hormone of the incretin system

In experimental wound healing models, TB-500 treatment increases capillary density by 40-50% while improving functional blood flow restoration, demonstrating translation of cellular angiogenic activity into meaningful tissue-level perfusion benefits