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It was observed that stress-induced activation of p53 in keratinocytes stimulated the release of chemicals that promote melanin production, potentially contributing to the senescence of melanocytes (84, 88, 89)

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Friedman BS, Santiago ML, Berkebile C, Metcalfe DD

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Gemss Asadi et al

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Takeaway: Patients may struggle with neuropsychiatric side effects

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