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GLP-1 receptor agonists are injectable (or oral for semaglutide tablets) and may produce greater weight loss, whilst SGLT2 inhibitors are oral and work by increasing glucose excretion in urine

All patients that satisfied these criteria were included, resulting in a final sample of 40 hypothyroidism (age mean 46 years, range 20 79 years, 4 males) and 12 CFS (mean age 43 years, range 23 68 years, 3 males) patients

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Sustained-release antioxidant hydrogel systems containing dissolved hydrogen have also been developed to enable prolonged topical delivery