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Summary of where we are on GLP-1 and anesthesia The highly regarded Anesthesia Patient Safety Foundation has taken a strong stance on the issues involving GLP-1RAs, advising considerable caution on our part when caring for patients using the drugs

So, if someone has a pervasive thyroid issue and they haven't addressed it appropriately and they lose weight because of a GLP 1, they go off of a GLP 1, they still have the same darn thyroid issue

43 Moreover, free fatty acids can aggregate into micelle-like structures with detergent properties, contributing to ischemia and local acidosis and ultimately triggering AP

If a bulk drug substance has impurities, potency drift, or microbial issues, a non-CGMP compounding pathway may not catch it consistently

It's not perfect he says, But its category four, the ultra-processed category, in which fiber has been removed, sugar added, and micronutrients are deficient, that provides the strongest correlation with chronic disease . Non caloric high intensity sweeteners So if excess amounts of added sugar are screwing up our metabolism, what should we replace it with