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HSP90 inhibitors have shown promise in preclinical models of autoimmune diseases such as arthritis and SLE by suppressing inflammatory signaling pathways

Among these, Helicobacter pylori infection is the most important since its prevalence has been estimated worldwide at 48%, despite wide regional discrepancies (Oceania 24% vs Africa 79%) (43)

These medications are peptide-based drugs administered subcutaneously, and their absorption, distribution, and metabolism are not significantly affected by oral magnesium supplementation