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The truncation reduces IGFBP binding similar to the LR3 modification, but DES IGF-1 retains a much shorter circulating half-life (typically reported in the 20 to 30 minute range) because the rest of the molecule remains susceptible to standard proteolytic clearance
Focus on consuming lean proteins, healthy fats, and plenty of fruits and vegetables
More research is needed on applying biotin topically
By Elie Dolgin Elie Dolgin is a science journalist in Somerville, Massachusetts
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