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The third limitation is that there may be the potential for numerous indirect effects or confounding

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No approach can guarantee complete preservation of muscle, and individual results vary

As a sympathomimetic amine, phentermine directly stimulates the release of norepinephrine and can cause significant heart rate increases, blood pressure elevation, and pronounced palpitations

MECHANISMS OF ACTION OF GLP-1 RAs AND MULTI-AGONIST THERAPIES Incretin-based therapies leverage the physiological roles of gut-derived peptide hormones, principally glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor (GCG) to address the multifaceted pathophysiology of MASLD