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Information specific to people with Down syndrome is included below

* Correspondence: Artnora Ndokaj, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Those considering such treatments should discuss potential risks and benefits with a qualified healthcare professional and ensure any B12 deficiency is properly investigated and managed according to established clinical protocols rather than through unregulated wellness programmes

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With sterile water, shelf life drops to forty-eight hours maximum