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The opposing physiological actions of ghrelin, compared to insulin and GLP-1, may justify the opposite direction of changes in response to cannabis in this study, i.e., increase in ghrelin levels, compared to decrease in insulin and GLP-1 levels
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Newer medicine options, including the sodium-glucose cotransport 2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists, have been shown to protect the heart and reduce the risk of many specific heart-related outcomes for people with type 2 diabetes
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