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Semaglutide and tirzepatide are relatively new developments in the GLP-1 space
A recent example is the SELECT trial finding that Ozempic (semaglutide) reduced cardiovascular events by 20% in overweight or obese adults with established heart disease and without diabetes
Unlike some older secretagogues, Ipamorelin is generally used because it promotes growth hormone release without significantly increasing cortisol or prolactin
S2CID 24723138
Its the most common variant in fact, more Americans have at least one copy of it than those who dont
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