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Typical cytologic findings are Hrthle cells and lymphocytic infiltration
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Gene expression analysis revealed Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased 2.1-foldall statistically significant changes indicating re-entrainment of disrupted circadian oscillations
It may appeal to clinicians and payers as an extension of semaglutide rather than a completely new receptor strategy
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