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I269T (a common missense variant of NPT1) mutations increase the maximum volume by increasing the turnover rate of the urate transport and output tomitigate gouty risk, but do not change NPT1 membrane expressions (Sakiyama et al., 2016)
[31] Thus, a deficiency in B 12 can cause accumulation of methyl-THF, mimicking folate deficiency
Kumar, P
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A comprehensive 2025 analysis published in the Proceedings of the National Academy of Sciences (PNAS) evaluated patient-reported outcomes for various treatments in post-viral dysautonomia and ME/CFS cohorts
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