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doi: 10.3389/fcvm.2025.1731127 Received 23 October 2025 Revised 15 November 2025 Accepted 28 November 2025 Published 15 December 2025 Volume 12 - 2025 Edited by Manfredi Tesauro, University of Rome Tor Vergata, Italy Reviewed by Angelo Maria Patti, University of Palermo, Italy Antonio Maria Labate, ASST Franciacorta, Italy Updates Copyright 2025 Tan, Yin and Lu