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It is important to understand that discovering high B12 levels should prompt investigation into potential underlying causes rather than focusing solely on the elevated vitamin itself

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The two recently FDA-approved ADCs (Adcetris by Seattle Genetics in 2011 and Kadcyla by Genentech in 2013) and the growing number of ADCs under clinical development have validated the idea of these magic bullets and are fueling rapidly increasing research interest and investment in ADCs globally 3

The delay in hydrogen peroxide formation, may reflect the non-enzymatic dismutation of superoxide anion as these measurements were performed in the absence of added superoxide dismutase