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They are functional, and they are driven primarily by the improvement in slow-wave sleep that follows increased GH pulsatility
Apoptosis induces tissue injury and fibrosis in MASH and many other chronic liver injuries, 79 establishing a rationale for inhibiting apoptosis as a therapeutic strategy
However, as an investigational compound, the full characterization of retatrutide's receptor pharmacology and its translation to long-term clinical outcomes remains to be established through ongoing Phase 3 clinical trials
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