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Retrieved July 21, 2018
First-in-human study of PC14586, a small molecule structural corrector of Y220C mutant p53, in patients with advanced solid tumors harboring a TP53 Y220C mutation
SAMe is central to transsulfuration (which produces glutathione, the brains major antioxidant (5)), and the synthesis of neuroregulatory polyamines (which have anti-inflammatory properties (6) and are involved in controlling cell differentiation and proliferation (7))
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