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The effect of SSTR2a on insulin secretion during hyperglycemia has been studied in SSTR2-knockout mice and in isolated cells but revealed only weak effects on insulin secretion (30, 43)
Why prolonged intermittent fasting is not recommended during GLP-1 therapy With GLP-1 treatment, the appetite is greatly reduced anyway
Although technically challenging, this should be further investigated, especially in light of the neuroimaging findings in ME/CFS, described in the following paragraphs
Recent data demonstrated that dietary fiber and short-chain fatty acids (SCFA), carbohydrates, and fats are potent stimulators of GLP-2 secretion
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