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Individuals on GLP-1 therapy with reduced appetite and food intake, need to ensure they are getting the right macronutrients (protein, carbohydrates, fats and fiber) and micronutrients (essential vitamins and minerals)
Pharmacol Res Perspect
Therefore, any relationship between GLP-1 therapy and muscle cramps is more likely to be indirect, mediated through secondary metabolic, nutritional, or fluid balance alterations rather than through direct receptor-mediated effects on muscle tissue
Monitor blood glucose levels if sweating occurs, particularly if taking GLP-1 medications alongside insulin or sulfonylureas
Indeed, the last three rows of Table 5 show that the up-regulation of CBS has exactly this effect and that the addition of oxidative stress makes the effect much stronger
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