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3.2 Epigenetic regulation Macrophage polarization is epigenetically regulated through DNA methylation, histone modifications, and non-coding RNAs, which collectively fine-tune gene expression and influence macrophage plasticity and disease roles ( Figure 2 )

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How Retatrutide Works (Mode of Action Explained Simply) Appetite & Satiety Control GLP-1 receptor activation reduces hunger signals from the brain, increases satiety, and slows gastric emptying