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Glutathione S-transferase in bone marrow metastases of disseminated neuroblastoma [PMID: 8027404] Laboratory literature summary: Glutathione S-transferase in bone marrow metastases of disseminated neuroblastoma
*Current Pharmaceutical Design*, 24(18), 19902001
The addition of nitro groups to specific tyrosine residues (Y198 and Y250) distorts the region HGF uses to dock with c-met, making it unable to activate satellite stem cells
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Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [8] [9]
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