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Kumar KJ, Saldanha K, Sushma K, et al
Phase I detoxification uses cytochrome P450 enzymes to break down toxins, but this process often creates highly reactive, intermediate metabolites that are actually more toxic than the original substance
Certain studies have found that when nerves are exposed to mercury, the myelin sheath (the fatty substance that surrounds the axon of some nerve cells and helps with electrical signaling) can become severely damaged, interfering with how nerves communicate
Endocrinology (2013) 154(1):48
The AGE-RAGE system may be responsible for the failure of ovulation characteristic of PCOS: in a model of human cell lines of granulosa, observed that the AGE interfere in vitro with the action of LH leading to altered follicular development and therefore the dysfunction ovulatory associated with PCOS [65]
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