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Some patients stabilize at their lowest therapeutic dose without tolerance development, continuing to lose weight steadily over 6-12 months
This result was explained by the authors as the lack of hepatocellular ballooning in a more consistent percentage of subjects within the pioglitazone group on initial biopsies as assessed after central review
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The researchers then used mouse experiments to test the relationship between T2DM, COVID-19 infection and pulmonary fibrosis
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