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Patients should seek immediate medical attention by calling 999 or attending the nearest Accident & Emergency department if they experience: Chest pain or pressure , particularly if radiating to the arm, jaw, or back Severe shortness of breath or difficulty breathing at rest Dizziness, light-headedness, or fainting (syncope) Irregular heartbeat with symptoms such as chest pain or severe dizziness Non-urgent but important symptoms that warrant contact with your GP or NHS 111 within 2448 hours include: Persistent palpitations occurring daily or interfering with activities Sustained rapid heart rate at rest New-onset heart racing associated with anxiety or panic symptoms Palpitations accompanied by persistent nausea, vomiting, or inability to maintain hydration Any cardiovascular symptoms in patients with pre-existing heart disease Your healthcare provider may arrange investigations such as an electrocardiogram (ECG) , blood tests to assess electrolytes and thyroid function, or 24-hour Holter monitoring to characterise any rhythm disturbance

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We therefore investigated a more generic approach consisting of generating steric blockade around the peptide to render it protease-resistant

This limits both hunger and interest in food, helping users lose weight, and helps control blood sugar levels

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