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In wildtype mice, optogenetic inhibition of GABAergic interneurons in the medial prefrontal cortex (mPFC) leads to cognitive deficits (29)
It analyzes pathway-level variants (FTO (rs9939609) and MC4R (rs17782313)) that relate to the biology involved, offering context for a conversation with your provider rather than a prediction
The mental health claims are extrapolations from animal data and mechanistic speculation
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