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Additional preclinical themes include angiogenesis (through endothelial cell migration and tube formation), modulation of inflammatory signalling, and reported effects on cardiac, dermal and neural tissue in animal models

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Talk to us first if you Are pregnant or breastfeeding Have an active or history of cancer Take medications that may interact Have a complex medical condition Are an athlete subject to testing (check your league's rules) This is general information, not medical advice

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Targeting these molecules with neutralizing antibodies or small-molecule antagonists (e.g., glycyrrhizin) has demonstrated BBB-stabilizing effects in vivo , including reductions in brain edema and vascular permeability (Lochhead et al., 2020