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A livello trascrizionale, PPAR attiva geni coinvolti nell'ossidazione degli acidi grassi (tra cui CPT1/2 e deidrogenasi per diverse lunghezze di catena), in particolare in condizioni di maggiore richiesta energetica e in specifiche fasi fisiologiche (es
These ingredients work synergistically to energize the skin and improve the look of body contours
doi: 10.1177/1933719117702247 48 LewisEDRichardCGorukSDellschaftNSCurtisJMJacobsRLet al
Placing those findings beside one another may suggest a broad biological narrative, but it does not demonstrate additivity or synergy
While nuclear factor erythroid 2-related factor 2 (NRF2) and CCAAT/Enhancer Binding Protein (CEBP) also contribute to a minor increase in CHAC1 transcription, their roles are less pronounced compared to ATF4 ( FIGURE 4 ATF4 and ATF3 regulate CHAC1 expression by binding to specific sites within its promoter, the ATF/cAMP response element (CRE) at position 267 and the ATF/CRE modifier (ACM) motif at 248
