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Methylmalonic Acidemias with Homocystinuria The genetic causes of methylmalonic acidemias with homocystinuria are due to defects in the methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria gene (MMACHC), the methylmalonic aciduria and homocystinuria, cblD type gene (MMADHC), LMBR1 domain containing 1 gene (LMBRD1
Bioavailability is still low, but it is useful for long-term management as this form is over-the-counter
2004;287:C123845
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