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Pharmacology Review: Drug mechanism, interactions, and special populations
Gallbladder complications Acute cholelithiasis (gallstones) was reported in at least one participant receiving 4.5 mg weekly cagrilintide in the phase 2 trial
Contraindications SYNJARDY and SYNJARDY XR are contraindicated in patients with: severe renal impairment (eGFR less than 30 mL/min/1.73 m2) [see Warnings and Precautions (5.1) and Use in Specific Populations (8.6)]
Compound-level evidence does not validate a stack
The impact of tirzepatide and glucagon-like peptide 1 receptor agonists on absorption of oral hormonal contraceptives
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