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Alternatives for microdosing GLP-1 medications include a slower titration phase, switching to a different medication, or managing the side effects with lifestyle modifications

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Additionally, AMG487 can effectively down-regulate inflammatory B cell signaling and exert an anti-arthritic effect in RA mice [69], indicating that CXCR3 is a potential therapeutic target for treating autoimmune diseases

In the large SELECT clinical trial, semaglutide 2.4mg (the active ingredient in Wegovy) was shown to reduce the risk of major cardiovascular events by 20% compared with placebo