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Considering the network that bi-directionally links obesity and insulin resistance in the pathogenesis of PCOS, it seems to be particularly appealing a new approach producing, at the same time, satisfactory and permanent weight loss, improvement in insulin resistance and in metabolic profile, with additional favourable outcomes on reproductive and cardiovascular systems (19)
The relationship between thyroid function, metabolic rate, and appetite regulation creates a complex clinical picture that requires careful evaluation before initiating weight loss medications
"Even the approved ones have real complications," said Dr
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