A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development
A peptide also cannot overcome ongoing overtraining, poor nutrition, uncontrolled blood sugar, untreated thyroid dysfunction, low testosterone when clinically relevant, vitamin or mineral deficiencies, or inadequate rest
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Plant Physiol 126:445462 Rahantaniana MS, Li S, Chatel-Innocenti G, Tuzet A, Issakidis-Bourguet E, Mhamdi A, Noctor G (2017) Cytosolic and chloroplastic DHARs cooperate in the induction of the salicylic acid pathway by oxidative stress