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Mol Cell Endocrinol (2016) 436:2409

The peptide appears to act antagonistically on opiate receptors, significantly inhibiting the development of both opioid and alcohol dependence in animal studies

Jnsson T, Granfeldt Y, Ahrn B, Branell UC, Plsson G, Hansson A, Sderstrm M, Lindeberg S

Most importantly, the limited amount of albumin leading to competition between icodec and semaglutide for albumin binding sites is only a local phenomenon occurring at the injection area

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